Bisphosphonate immobilization of the titanium implant surface and the functionality and adhesion protein binding method

摘要

Titanium implant was covered with a thin film of calcium phosphate method and immersed in a bisphosphonate solution [summary] the titanium implants were injected with [configuration] calcium ions, immobilized as a non-eluting bisphosphonates on the surface of the titanium implant how to fixed as-eluting bisphosphonates on the surface of the titanium implant was immersed in bisphosphonate solution, how to join the adhesion protein and functionality for bisphosphonate which is immobilized. Suppress the tartar and plaque adhesion by immobilization of bisphosphonates to [effect] oral implant fixture parts, bacterial infections, inhibit the attachment of periodontal disease-causing bacteria in particular, bone formation rate and metabolic activity of bone formation bone resorption and increased also suppressed, By making further combines the functionality of protein or adhesive raw protein to bisphosphonates, bone-inducing ability to bone formation is granted from where there is no bone, for the titanium implant treatment, breakthrough invention was not in conventional is.