STABLE SOLID AGENT CONTAINING ORAL CAVITY DISINTEGRATION TYPE VOLATILE MEDICINE AND ITS PRODUCTION

摘要

PROBLEM TO BE SOLVED: To obtain a stable volatile medicine-containing solid agent having proper solubility and disintegration in oral cavity, forming a dissolved material or suspension in salvia. ;SOLUTION: This solid agent comprises a volatile medicine, lactose, 0.05-3.0 wt.% based on solid component of agar and 0.025-2.5 wt.% of one or more components selected from the group consisting of a polyvinyl pyrrolidone, methyl cellulose, hydroxypropyl cellulose and hydroxypropylmethyl cellulose and is produced by dissolving and/or dispersing these components into water and removing the solvent.;COPYRIGHT: (C)1998,JPO