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Substituted 9-amino-tetrahydroacridine and related compounds

机译:取代的9-氨基-四氢ac啶及相关化合物

摘要

There are disclosed compounds having the formula CHEM wherein n is 1-4; X is alkyl of 3-18 carbon atoms, cycloalkyl of 3-7 carbon atoms or cycloalkylloweralkyl; R is hydrogen, loweralkyl or loweralkylcarbonyl; R1 is hydrogen, loweralkyl, loweralkylcarbonyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, oxygen-bridged arylloweralkyl or oxygen-bridged diarylloweralkyl; stereo isomers thereof and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory, methods for synthesizing them, and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound.
机译:公开了具有式的化合物,其中n为1-4; X是3-18个碳原子的烷基,3-7个碳原子的环烷基或环烷基低级烷基; R为氢,低级烷基或低级烷基羰基; R1是氢,低级烷基,低级烷基羰基,芳基,二低级烷基氨基低级烷基,芳基低级烷基,二芳基低级烷基,氧桥联的芳基低级烷基或氧桥联的二芳基低级烷基;用于增强记忆的其立体异构体及其药学上可接受的酸加成盐,其合成方法以及包含有效增强记忆量的此类化合物的药物组合物。

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