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Bioassay null in order to test the activity which mediates by the type blood platelet origin growth factor receptor
Bioassay null in order to test the activity which mediates by the type blood platelet origin growth factor receptor
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机译:生物测定法无效以测试由类型血小板起源生长因子受体介导的活性
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摘要
PURPOSE: To determine the activity intermediate by a receptor in a cell by bringing an analogous molecule of a platelet derived growth factor(PDGF) into contact with the receptor formed by the cell which is transformed by a DNA segment which encodes a PDGF receptor (-R) protein of type β. ;CONSTITUTION: A T11 genomic clone, a human cDNA clone, etc., are used in a DNA segment. A molecule which is assumed to be an analog of PDGF is brought into contact with a receptor formed by a cell transformed by the DNA segment which encodes a PDGF-R protein of type β. The cell is preferably a mammalian cell and contains a yeast cell and a bacteria cell. Next, an amount of biological activity intermediated by PDGF-R of type β in the cell is determined to test the activity of a latent analog of PDGF.;COPYRIGHT: (C)1996,JPO
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