An in vitro Method '' '' to inactivate pathogens containing RNA in Mammalian blood and blood components of mammals and in the same materiautilizada composition

摘要

An in vitro method to inactivate pathogens containing RNA in Mammalian blood and blood components of mammalsWhere the material component of a Protein of the same treaty must be introduced in a Mammal which is characterized in that it comprises: a) Interact in vitro more elected grUpo which consists of Mammalian blood and blood components of mammals, suspected of containing a pathogenic RNAI made with a unacomposiciu00f3n comprising: (i) which has a portion that is a Binder for Binding Nucleic Acid interacts with the acid nucleicodel pathogen through interactionNon Covalent; (2) a portion that forms a Covalent Complex with the Nucleic Acid of the pathogen, the group that consists of a chosen intermediary Mustard, Mustard,And a equifalente Mustard; and (3) greater efficiency of inactivation by R17 a compound II contains a selected portion of a Broker, Mustard, Mustard,And an equivalent of Mustard,But lacks the portion of Binder deenlazamiento Nucleic Acid; (i) where the concentration of compound i in the method is used in the inactivation of at least L 1 logPrimary pathogen present in Blood, if any; and (b) maintain the treated material or a Protein derived from the same unmamu00edfero for their Liberation.