首页> 外国专利> Use of tricyclic derivatives of 1,4-hydroxy-1,4-oxide-1H-naphthalene new compounds obtained and their application in therapy

Use of tricyclic derivatives of 1,4-hydroxy-1,4-oxide-1H-naphthalene new compounds obtained and their application in therapy

机译:1,4-羟基-1,4-氧化物-1H-萘新化合物的三环衍生物的用途及其在治疗中的应用

摘要

The invention concerns the therapeutic use of tricyclic salts and their pharmaceutically acceptable salts having the general formula:in which:A is either a sulfur atom, an oxygen atom, or an R3N radical where R3 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring.R1 is either a C1-C5 alkyl radical,or an R4NH radical where R4 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring,or an aromatic ring that may or may not be substituted by one or more acceptor or donor groups, or a heteroaromatic ring having one or more heteroatoms, which may or may not be substituted by acceptor or donor groups.R2 is a hydrogen atom, halogen atom, a C1-C5 alkyl radical, an oxygen atom that may or may not be substituted by a C1-C5 alkyl radical, or an NR5R5, radical where R5 and R5, are, independently of each other, a hydrogen atom, an oxygen atom or monovalent C1-C5 organic radicals.
机译:本发明涉及具有以下通式的三环盐及其药学上可接受的盐的治疗用途:其中:A是硫原子,氧原子或R3N基团,其中R3是氢原子,C1-C5烷基R 1是C 1 -C 5烷基,或R 4 NH基团,其中R 4是氢原子,C 1 -C 5烷基,或取代或未取代,或取代或未取代的芳族环。芳环,或取代或未取代的杂芳族环,或可以被一个或多个受体或供体基团取代或不被其取代的芳族环,或具有一个或多个可以被或可以不被受体取代的杂原子的杂芳族环R 2是氢原子,卤素原子,C 1 -C 5烷基,可以被或可以不被C 1 -C 5烷基取代的氧原子或NR 5 R 5,其中R 5和R 5是:彼此独立原子,氧原子或一价C1-C5有机基团。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号