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Modulation of cytokine expression in th1 / th2 by ribavirin and ribavirin analogues in activated lymphocytes
Modulation of cytokine expression in th1 / th2 by ribavirin and ribavirin analogues in activated lymphocytes
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机译:利巴韦林和利巴韦林类似物在活化淋巴细胞中对th1 / th2中细胞因子表达的调节
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摘要
Ribavirin3 is administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. In particular, Ribavirin3 is used to suppress Th2-mediated T cell responses and promote Th1-mediated T cell response. In other aspects of the invention, one or more Ribavirin3 analogs are administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. The Ribavirin3 analog(s) may be used to suppress or enhance Th1 or Th2-mediated T cell responses.
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