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Transdermal matrix system based on EVA for administration of an estrogen and / or a progestagen
Transdermal matrix system based on EVA for administration of an estrogen and / or a progestagen
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机译:基于EVA的透皮基质系统,用于雌激素和/或孕激素的给药
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摘要
Self-adhesive transdermal matrix material for percutaneous admin. of a hormone comprises (1) a support and (2) a self-adhesive matrix consisting of (by wt.); (a) 40 - 60 pts. ethylene-vinyl acetate copolymer (EVA); (b) 5 - 20 pts. cellulose deriv. (I); (c) 35 - 55 pts. at least one of crotamiton (II); N-substd. 2-pyrrolidones of formula (III) or 12-20C aliphatic alcohol (IV) and (d) 0.01-7 pts. oestrogenic and/or progestational hormone. R = 1-15C alkyl, cyclohexyl or 2-hydroxyethyl.
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