POLYPEPTIDES CONTAINING PROTEIN GAX DOMAINS PARTICIPATING IN SUPPRESSING TRANSCRIPTIONS AND / OR INTERACTING WITH OTHER PROTEINS, RELATED NUCLEIN ACIDS

摘要

The present invention relates to polynucleotides, including GAX domains involved in the biological activity of GAX. These can be, in particular, domains that are involved in the interaction of GAX with other molecules, or domains that are involved in biological activity. The invention also relates to chimeric molecules containing a functional domain of GAX. It also relates to the use of GAX to suppress gene expression, as well as to the use of compounds inhibiting the interaction of GAX with certain cellular partners to alter GAX activity. It also refers to the screening method and / or definition of GAX cellular partners. The international application was published along with an international search report.