首页>
外国专利>
AN ANTIVIRALLY ACTIVE PHARMACEUTICAL OIL-IN-WATER EMULSION CONTAINING 9-/(2-HYDROXYETHOXY)METHYL/GUANINE (ACYCLOVIR) OR A SALT OR ESTER THEREOF
AN ANTIVIRALLY ACTIVE PHARMACEUTICAL OIL-IN-WATER EMULSION CONTAINING 9-/(2-HYDROXYETHOXY)METHYL/GUANINE (ACYCLOVIR) OR A SALT OR ESTER THEREOF
展开▼
机译:包含9-/(2-羟基乙氧基)甲基/鸟嘌呤(无环藻酸酯)或其盐或酯的抗病毒活性药水乳液
展开▼
页面导航
摘要
著录项
相似文献
摘要
An antivirally active pharmaceutical oil-in-water emulsion containing 9-((2-hydroxyethoxy)methyl)guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.
展开▼