The use of a compound of formula (I) wherein R1 is H; C1-C3 alkyl; C1-C3 perfluomalkyl; or C3-C5 cycloalkyl; R2 is H; optionally substituted C1-C6 alkyl; C1-C3 pefluoroalkyl; or C3-C6 cycloalkyl; R3 is optionally substituted C1-C6 alkyl; C1-C6 perfluoroalkyl; C3-C5 cycloalkyl; C3-C6 alkenyl; or C3-C6 alkynyl; R4 is optionally substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkanoyl, (hydroxy)C2-C4 alkyl or (C2-C3 alkoxy)C1-C2 alkyl; CONR5R6; CO2R7; halo; NR5R6; NHSO2NR5R6; NHSO2R8; SO2NR9R10; or phenyl, pyridyl, pyrimidinyl, imidazolyl, oxazolyl, thiazolyl, thienyl or triazolyl any of which is optionally substituted with methyl; R5 and R6 are each independently H or C1-C4 alkyl, or together with the nitrogen atom to which they are attached form an optionally substituted pyrrolidinyl, piperidino, morpholino, 4-N(R11)-piperazinyl or imidazolyl group; R7 is H or C1-C4 alkyl; R8 is optionally substituted C1-C3 alkyl; R9 and R10 together with the nitrogen atom to which they are attached form an optionally su
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机译:R 1为H的式(I)化合物的用途; C1-C3烷基; C1-C3全氟烷基;或C3-C5环烷基;或R2为H;任选取代的C 1 -C 6烷基; C1-C3全氟烷基;或C3-C6环烷基;或R3是任选取代的C1-C6烷基; C1-C6全氟烷基; C3-C5环烷基; C3-C6烯基;或C3-C6炔基;或R4是任选取代的C1-C4烷基,C2-C4烯基,C2-C4烷酰基,(羟基)C2-C4烷基或(C2-C3烷氧基)C1-C2烷基; CONR5R6; CO 2 R 7;光环; NR5R6; NHSO 2 NR 5 R 6; NHSO 2 R 8; SO2NR9R10;或苯基,吡啶基,嘧啶基,咪唑基,恶唑基,噻唑基,噻吩基或三唑基,它们中的任何一个任选地被甲基取代;或R5和R6各自独立地为H或C1-C4烷基,或与它们所连接的氮原子一起形成任选取代的吡咯烷基,哌啶子基,吗啉代,4-N(R11)-哌嗪基或咪唑基。 R7是H或C1-C4烷基; R8是任选取代的C1-C3烷基; R9和R10与它们所连接的氮原子一起形成一个可选的su
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