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Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
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机译:包含低剂量活性成分油和能够结合水的赋形剂的固体药物组合物及其制备方法
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摘要
The invention concerns a solid pharmaceutical composition comprising less than 7% by weight of an oil or oily substance, a low dosage active ingredient, and a water insoluble non-cross-linked polymeric excipient capable of binding water and having a mean particle size greater than 150 mu m. The composition can be obtained by a simple procedure comprising mixing the water insoluble non-cross-linked polymeric excipient capable of binding water and the active ingredient, which is dissolved or dispersed in an oil or an oily substance, in an aqueous dispersion thereof, or in water.
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