首页>
外国专利>
PURIFIED ANTIGENIC COMPLEX FOR RAISING ANTIBODY RESPONSE AGAINST PORPHYROMONAS GINGIVALIS
PURIFIED ANTIGENIC COMPLEX FOR RAISING ANTIBODY RESPONSE AGAINST PORPHYROMONAS GINGIVALIS
展开▼
机译:纯化的抗原复合物,可增强针对齿龈卟啉单胞菌的抗体反应
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to the PrtR-PrtK cell surface protein of Porphyromonas gingivalis in particular a multimeric cell associated protein complex comprising the PrtR and PrtK proteins. There is provided a substantially purified antigenic complex for use in raising an antibody response directed against Porphyromonas gingivalis. The complex comprises at least one multimeric protein complex of arginine-specific and lysine-specific thiol endopeptidases each containing at least one adhesin domain. The complex has a molecular weight of greater than about 200 kDa. The invention also relates to pharmaceutical compositions and associated agents based on said complex for the detection, prevention and treatment of Periodontal disease associated with P. gingivalis.
展开▼