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New pirrolcarboxamidas merged; a new class of GABA Brain receptor ligands
New pirrolcarboxamidas merged; a new class of GABA Brain receptor ligands
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机译:新的Pirrolcarboxamidas合并;一类新的GABA脑受体配体
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摘要
Refers to a compound of formula (i) or its Salts, where G is a compound of formula (a), Q is - 2 - phenyl - 2 - 3 - tienilo piridilo mono or di substituted with Hydroxy is Halogen or Halogen; T, h,Amino hydroxyl or alkoxy C1 - C6; W is n or S - cr7r8; R7 and R8 is H, alkyl radical or together form a cyclic C3 - C7 hydroxyl; X is H, alkyl or alkoxy; Z is cycloalkyl Hydroxy, alkoxy, C3 - C7Amino, mono or dialquilamino or nr9cor10; R9 and R10 is H, alkyl or cycloalkyl C3 - C7 or joins W Z, Q from a Ring of 1 - 6, - (CH2) - (CH2) K, - M, - N - (CH2) where K, M and N there are 0 - 3; R3R4, R5 and R6 are h, alkyl of C1 - C6, cor11, co2r11; R11 is c1-c6 alkyl, cycloalkyl - C3 - C7, conr12r13; R12 and 13 h, alkyl, cycloalkyl C3 C1 - C6, C7, phenyl -, 2 -, 3 -,4 - piridilo; or nr12r13 form morfolinilo, piperidinilo, pirrolidinilo or N - alquilpiperazinilo; R3 and R4 together form a cycle C3 - C7; R5 and R6 together form a cycle of C3 - C7; alkyl R3, R4,R5 or R6 can be substituted with Hydroxy or mono or dialquilamino C3 - C7.Compound I can be useful to treat Anxiety Disorders, Attention, sleep and Overdose Of benzodiazepine type Drugs, improve Memory
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