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PROCESS FOR THE PREPARATION OF TABLETS AND GRANULATION CONTAINING AS ACTIVE SUBSTANCE SODIUM 2-MERCAPTOETHANOSULPHONATE (MESNA)
PROCESS FOR THE PREPARATION OF TABLETS AND GRANULATION CONTAINING AS ACTIVE SUBSTANCE SODIUM 2-MERCAPTOETHANOSULPHONATE (MESNA)
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机译:包含活性物质2-巯基乙醇磺酸钠(MESNA)的片剂和制粒剂的制备过程
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摘要
A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other agents. The tablets contain: 0.01-1 parts by weight of a binding agent 0.03-0.4 parts by weight of a disintegrant 0.01-0.2 parts by weight of a lubricant and 0.1-1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05-30 parts by weight of a conventional physiologically acceptable effervescent mixture.
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