ENZYMATIC PROCESSES FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF COMPOUNDS USEFUL AS INTERMEDIARIES IN THE PREPARATION OF TANAXES

摘要

ENZYMATIC PROCESSES FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF COMPOUNDS USEFUL AS INTERMEDIATES IN THE PREPARATTON OF TAXANES Methods for the enzymatic resolution ofmixtures of enantiomers, such as [err]-lactamcompounds, which may be employed as intermediatesin the preparation of taxanes bearing a C-13sidechain containing a heterocyclic or cycloalkylgroup, the latter useful in the pharmaceuticalfield.