首页> 外国专利> CONNECTIVES WITH SELECTIVE EFFECT FOR RETINOID X RECEPTORS, AND MEANS FOR CONTROLLING FOR PROCESSES CONCERNED BY RETINOID X RECEPTORS

CONNECTIVES WITH SELECTIVE EFFECT FOR RETINOID X RECEPTORS, AND MEANS FOR CONTROLLING FOR PROCESSES CONCERNED BY RETINOID X RECEPTORS

机译:维甲酸X受体具有选择性作用的连接物,以及维甲酸X受体所考虑的过程的控制方法

摘要

Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and polyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
机译:使用类视色素样化合物对类视色素X受体介导的过程进行调节的化合物,组合物和方法,其优先选择视黄酸受体(RAR)的亚类的成员,对类视色素X受体(RXR)的子类具有选择性的活性。这种化合物的实例是双环苄基,吡啶基,噻吩,呋喃基,吡咯和包括碳环多烯酸的多烯酸衍生物。所公开的方法采用化合物来调节类视黄醇X受体选择性介导的过程。

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