INHIBITION OF THE HYPERPLASIA OF THE INTIMATE EMPLOYING ANTIBODIES OF RECEPTORS OF THE GROWTH FACTOR DERIVED FROM PLATELETS.

摘要

METHODS OF INHIBITION OF INTIMATE HYPERPLASIA ARE DESCRIBED IN THE VASCULATURE OF MAMMALS, INCLUDING PRIMATES. THE METHODS INCLUDE THE ADMINISTRATION TO THE MAMMAL OF AN ANTI-PDGF RECEPTOR ANTIBODY, LIKE AN ANTI-PDGF-ALPHA RECEPTOR ANTIBODY OR AN ANTI-PDGF-BETA RECEPTOR ANTIBODY. THE METHODS ARE USEFUL IN REDUCING INTIMATE HYPERPLASIA DUE TO, FOR EXAMPLE, VASCULAR INJURIES RESULTING FROM ANGIOPLASTY, ENDARTERECTOMY, REDUCTION ATTERECTOMY, OR ANASTOMOSIS OF A VASCULAR GRAFT.