Dichloride process for preparing 5-Amino-2,4,6-triiodoisophthalic by chlorinating the corresponding acid in the presence of a tertiary amine salt or quaternary ammonium salt.

摘要

It DESCRIBED ONE FOR PREPARATION PROCESS dichloride acid 5 - AMINO - 2,4,6 - TRIIODOISOFTALICO by chlorinating OF 5 - AMINO - 2,4,6 - TRIIODOISOFTALICO with thionyl chloride presence of a suitable solvent and TERTIARY OR amine quaternary ammonium salt in a molar ratio of 1: 1 to 1: 2 with respect to 5 - AMINO - 2,4,6 TRIIODOISOFTALICO. Dichloride 5 - AMINO - 2,4,6 TRIIODOISOFTALICO is an intermediate useful for preparing iodinated contrast agents.