CALCIUM PHOSPHATE HYDROXYAPATITE PRECURSOR AND METHODS FOR MAKING AND USING THE SAME

摘要

Calcium phosphate composition that are particularly useful and unique as orthopedic and dental cements and remineralizers, aswell as methods and kits for their use, and the resulting products are disclosed. The compositions comprise tetracalcium phosphate whichhas been prepared from a mixture with a calcium to phosphorous ratio of less than 2, or prepared and maintained under substantiallyanhydrous conditions prior to use or, preferably, both. The novel compositions are converted substantially to hydroxyapatite upon setting,are substantially gradually resorbable and replaced by bone when implanted in contact with living bony tissue, and offer distinct advantagesin terms of cement strength, setting time and reliability and other properties.