VITAMIN D3 DERIVATIVES AND REMEDIES FOR INFLAMMATORY RESPIRATORY DISEASES PREPARED FROM THE SAME

摘要

Vitamin D3 derivatives represented by general formula [1] and a process forproducing the same: wherein R1 and R2 represent each hydrogen, trialkylsilyl,etc.; R3 and R4 represent each hydrogen, hydroxy, etc.; R5 to R8 representeach hydrogen, hydroxy, alkyl or acyloxy; R9 represents hydrogen, hydroxy,alkyl or alkylthio; R10 represents hydrogen, alkyl or alkyloxy; A and Brepresent each hydrogen, hydroxy, etc.; X and Y represent each carbonyloxygen, or one of X and Y represents hydrogen while another representshydroxy, etc.; and n and m are each 0 to 2. These compounds are usable as theactive ingredients of remedies for inflammatory respiratory diseases,malignant tumors, articular rheumatism, osteoporosis, diabetes mellitus,hypertension, baldness, acne, psoriasis, and dermatitis.