PEPTIDE EPITOPES RECOGNISED BY ANTIFILAGGRIN AUTOANTIBODIES IN SERUM FROM RHEUMATOID ARTHRITIS PATIENTS

摘要

the invention relates to peptides comprising epitopes recognized byantifilaggrine autoantibodies present in the serum of patients withrheumatoid arthritis (ra). they include an epitope motifbased on the tripeptide residue citrulline. the invention is alsoon the artificial antigens containing the epitopes, and theirthe use of this antigen for the diagnosis of rheumatoid arthritis.