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Low molecular weight compounds administered together with anti-cancer agents to treat cancer and pharmaceutical compositions thereof
Low molecular weight compounds administered together with anti-cancer agents to treat cancer and pharmaceutical compositions thereof
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机译:与抗癌药一起给药的低分子量化合物及其药物组合物
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摘要
The present invention is directed to novel disulfides and thiols that are of up to about eighteen amino acids. One example, is a compound of the formula (1): A-B-C-S-S-D-E-F, wherein: A and F are selected from the group consisting of hydrogen, an amino acid, a dipeptide, a tripeptide, a modified polypeptide up to three amino acids long, and a carbobenzoxy groups, B and E are selected from the group consisting of an amino acid, a dipeptide, a tripeptide, and a modified polypeptide comprising up to and including three amino acids, C and D are selected from the group consisting of a modified polypeptide and a polypeptide comprising up to and including three amino acids, and S is the sulfur atom in the modified polypeptide and the polypeptide in C and D.
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