BONE-RESORPTIVE CYTOKINE INHIBITOR CONTAINING DIENOGEST AS THE ACTIVE INGREDIENT

摘要

An inhibitor of production and/or secretion of IL-1, IL-6 or TNF-α and a preventive and/or remedy for hypercalcemia accompanying rheumatoid arthritis, asteoarthritis or malignant tumor, characterized by containing dienogest or a solvate thereof as the active ingredient, while utilizing novel cytokine production inhibitory activities of dienogest or a solvate thereof.