PYRIMIDIN 3-OXIDE COMPOUNDS SUITABLE FOR THE TREATMENT OF PATHOLOGIES OF THE SKELETAL MUSCLE, IN PARTICULAR FOR THE TREATMENT OF THE HYPOKALEMIC PARALYSIS

摘要

The present invention relates to pyrimidin 3-oxyde compounds particularly useful for the production of a medicament for the treatment of pathologies of the muscular skeletal apparatus. Among these compounds, the 6-[1-Piperidinyl]pyrimidin-2,4-diamin 3-oxide is particularly effective in the treatment of the familial primary hypokalemia (HOPP) and in the secondary forms induced by drugs, toxins, gastrointestinal K+ loss or by free K+ diet.