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LIGAND GROWTH FACTORS THAT BIND TO THE erbB-2 RECEPTOR PROTEIN AND INDUCE CELLULAR RESPONSES
LIGAND GROWTH FACTORS THAT BIND TO THE erbB-2 RECEPTOR PROTEIN AND INDUCE CELLULAR RESPONSES
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机译:绑定到erbB-2受体蛋白并诱导细胞反应的配体生长因子
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摘要
The present invention relates to erbB-2 ligands and function derivatives thereof which are capable of binding to the erbB-2 transmembrane protein but fail to bind to epidermal growth factor receptor. The present invention further pertains to anti-ligand molecules capable of recognizing and binding to the erbB-2 ligand molecule and to screening assays for such ligands. The present invention additionally relates to uses for the erbB-2 ligand, the anti-ligand molecules and the screening assays.
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