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Target cell specific vectors for the insertion of genes into cells, medicament containing such vectors and their use

机译:用于将基因插入细胞的靶细胞特异性载体,包含该载体的药物及其用途

摘要

Cell-specific vector (A) for introduction of at least one gene (I) into the cells of an organism comprises: (a) non-viral carrier for (I); (b) ligand (II) that binds specifically to target cells; (c) a fusion (i.e. fusogenic) protein (III) for penetration of (A) into target cell cytoplasm and (d) the gene (I).
机译:用于将至少一个基因(I)引入生物体细胞的细胞特异性载体(A)包括:(a)(I)的非病毒载体; (b)与靶细胞特异性结合的配体(II); (c)融合蛋白(III),其用于使(A)渗透到靶细胞的细胞质和(d)基因(I)。

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