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PLATELET-ENDOTHELIAL CELL ADHESION MOLECULE-1 COMPOSITIONS AND METHODS
PLATELET-ENDOTHELIAL CELL ADHESION MOLECULE-1 COMPOSITIONS AND METHODS
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机译:血小板-内皮细胞粘附分子1的组成和方法
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摘要
Novel, substantially isolated isoforms of human platelet-endothelial cell adhesion molecule-1's, DNAs coding for transcripts that encode the novel isoforms and others, including a previously identified soluble isoform, methods of using such DNAs to make isoforms by expressing the DNA's, and promoter segments controlling transcription of human platelet-endothelial cell adhesion molecule-1 genes are provided. The novel isoforms differ from the complete human platelet-endothelial cell adhesion molecule-1's in lacking one or more segments near the C-terminus encoded by exons 10-15 of the genes for the full length molecules and arise in vivo from alternative splicing of the transcript from the genes.
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