Benzo(b)thiophene derivatives for inhibiting detrimental side-effects due to GnRH or GnRH agonist administration

摘要

The use of a compound of formula I wherein R¹ and R³ are, independently, -H, -CH₃, -CO(C₁-C₆ alkyl), or -COAr, where Ar is optionally substituted phenyl;R³ is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; ora pharmaceutically acceptable salt or solvate thereof, in the preparation of a pharmaceutical formulation for inhibiting detrimental side-effects of GnRH or a GnRH agonist in a mammal.