Actinomyces pieogenes and Actinomyces piegenses / Pejo bacterium necropolium vaccine for immunization of cows and sheep

摘要

The novel inoculum of the invention for administration to ruminants such as cows or sheep is for reducing the incidence of liver abscess and / or foot decay and for immunizing animals. According to one aspect of the present invention there is provided an A. pyogenes-inducible vaccine containing an inert cell culture product (for example, a supernatant made from cells) of A. pyogenes cell culture and a suitable carrier. According to another aspect of the present invention there is provided a multivalent vaccine comprising at least a first and a second bacterial component and a carrier, wherein the first component is composed of an inert cell culture product of A. pyogenes and the second component is inert of F. necropoleum Cell culture products. The inoculum of the present invention is particularly useful when the ruminant is infected with F. necropoleum causing liver abscess and / or foot decay, for example when such ruminants are treated with antibiotics regularly or contain a high proportion of grains It is especially useful when concentrated feed is supplied.