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FAB region genes and their nucleotide sequences of mouse aggregated monoclonal antibodies against human blood cells
FAB region genes and their nucleotide sequences of mouse aggregated monoclonal antibodies against human blood cells
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机译:小鼠抗人血细胞聚集单克隆抗体的FAB区基因及其核苷酸序列
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摘要
The present invention relates to Fab sites of mouse aggregated monoclonal antibodies against human blood cells, cDNA genes encoding them and their nucleotide sequences. Specifically, the present invention relates to Fab sites of mouse aggregated monoclonal antibodies against human blood cells, heavy and light cDNA genes encoding them, their base sequences and plasmid vectors comprising the same, wherein the genes are in blood such as HIV. And humanized antibodies for diagnosing antigen.
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机译: 结合人CD20的人单克隆抗体,该抗体能够在存在补体的情况下诱导表达CD2的细胞的补体依赖性细胞毒性,并且包含根据EP1558648B1的权利要求1的轻链和重链CDR区, i),(ii)(a)和(iii)(SEQ ID Nos.16、17、18、13、14和15),特别是包含轻链和重链可变区序列的抗体根据EP1558648B1的权利要求4(SEQ ID Nos.4和2),特别是ofatumumab