DRUG DELIVERY SYSTEM FOR THE SIMULTANEOUS DELIVERY OF DRUGS ACTIVATABLE BY ENZYMES AND LIGHT

摘要

In a composition for treating cancer tissue of a warm-blooded animal comprising both an anticancer agent and a photoactive ink attached to a copolymer carrier, (a) a copolymer carrier comprising an anticancer agent and a photoactive nutrient, (b) a copolymer carrier attached to an anticancer agent, A copolymer carrier mixture of another copolymer to which the photoactive drug is attached, and (c) (a) and (b) the composite case. The anticancer agent is attached to the polymer carrier by the side chain, which is stable in the bloodstream of warm-blooded animals but can be hydrolyzed by intracellular lysosomal enzymes, and the photoactive drug is also attached by the same degradable side chain or non-degradable attachment. The polymer carrier optionally has a target material. Induction of polymerizable macromolecules into target cancer cells by cell absorption can reduce side effects caused by general drugs. The anticancer agent allows time delays for infusion for the absorption of selective copolymers in cancer tissues in order to take effect. Light sources of the appropriate wavelength and energy activate the photoactive drug. The combined effect of anticancer drugs and photoactive drugs can be good for cell destruction with reduced amounts and reduced side effects.