MODIFIED SUBTILYSINE, DNA ENCODING MODIFIED SUBTILYSINE, EXPRESSION VECTOR ENCODING DNA AND STRAIN OF HOST CELL CULTURE

摘要

FIELD: molecular biology, biochemistry. SUBSTANCE: invention relates to the modified carbonylhydrolase. In amino acid sequence of subtilysine 76 amino acid residues and at least one additional amino acid residue are substituted. EFFECT: enhanced proteolytic activity of enzyme by modification. 11 cl, 7 tbl, 24 dwg, 7 ex