首页> 外国专利> The use of pharmaceutical preparations, the particles, vesicles or polymers as well as use non-steroidal antirheumatics and / or platelets unit ion inhibitors for the representation of the vessels, lymph node and of the bone marrow contain

The use of pharmaceutical preparations, the particles, vesicles or polymers as well as use non-steroidal antirheumatics and / or platelets unit ion inhibitors for the representation of the vessels, lymph node and of the bone marrow contain

机译:使用药物制剂,颗粒,囊泡或聚合物以及使用非甾体类抗风湿药和/或血小板单位离子抑制剂来代表血管,淋巴结和骨髓

摘要

The invention relates to a pharmaceutical preparation containing at least one particulate, vesicular or polymer diagnostic reagent combined with at least one nonsteroidal antirheumatic agent and/or thrombocyte-agglutination inhibitor. The invention also describes the possibility of improving the concentration and homogeneity of contrast media distribution of particles, vesicles or polymers in pharmaceutical preparations in lymph nodes by combining the particular vesicular or polymer contrast media with non steroidal antirheumatic agents or thrombocyte-agglutination inhibitors. This combination results in an extended residence time in the vascular area (longer blood half time period) so that the use thereof as contrast media in diagnostic representation of the vascular system is also improved. In order to improve the diagnostic value of iron oxides as a result of improved concentration in lymph nodes or extended blood half time periods, it makes little difference if the non-steroidal antirheumatic agent of the thrombocyte-agglutination inhibitor is administered shortly before applying the contrast medium or together with a pharmaceutical preparation. According to the invention, the application can occur in an inverse order.
机译:本发明涉及一种药物制剂,该药物制剂包含至少一种颗粒,囊泡或聚合物诊断试剂以及至少一种非甾体类抗风湿剂和/或血小板凝集抑制剂。本发明还描述了通过将特定的囊泡或聚合物造影剂与非甾体类抗风湿剂或血小板凝集抑制剂组合来改善淋巴结中药物制剂中的颗粒,囊泡或聚合物的造影剂分布的浓度和均匀性的可能性。这种组合导致在血管区域中的停留时间延长(血液半衰期更长),从而也改善了其在血管系统的诊断表示中作为造影剂的用途。为了改善淋巴结中的浓度或延长血液半衰期而提高氧化铁的诊断价值,如果在应用造影剂前不久服用血小板凝集抑制剂的非甾体类抗风湿剂,则没有什么区别。介质或与药物制剂一起使用。根据本发明,应用可以以相反的顺序进行。

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