High - functionalized, with polyethylene glycol grafted, polystyrene - carrier

摘要

This invention provides novel polymers and graft copolymers of poly(ethylene oxide) and methods for their preparation and purification. The invention provides graft copolymers of a backbone polymer comprising poly(methylstyrene) and side chain polymers of poly(ethylene oxide). The graft copolymers have up to three poly(ethylene oxide) chains per methylstyrene unit in the backbone. The poly(ethylene oxide) chains are attached to the backbone polymer via a 1,3-dioxyprop-2-yl linking group. The polymers of this invention are made by reaction of a 1,3-dicarbonyl nucleophile with a backbone polymer having a leaving group and subsequent modification. The purification methods comprise treating the polymers with a polar protic solvent.