Density star-shaped polymers for the calibration / classification of reactive sub-micron - openings

摘要

In a substance such as a membrane, a cell or virus having at least one aperture of a diameter of about 10,000 Angstroms or less, a process for measuring and characterizing the diameter of the aperture, comprising: PP(a) contacting the substance with a solution of a plurality of dense star polymers;PP(b) passing through or into the aperture at least one dense star polymer having a molecular diameter of about equal to or less than the diameter of the aperture; andP P(c) calculating the diameter of the aperture from measurements of either those dense star polymers passing therethrough or thereinto the aperture, of those dense star polymers not passing therethrough or thereinto, or of the combined measurements of those dense star polymers passing therethrough or thereinto the aperture and those not passing therethrough or thereinto.