1 - Phenoxy - 3 - n - alkyl amino propane - 2 - ol halogenated derivatives, as a marker for beta - adrenergic heart muscle receptors, and as a beta blockers

摘要

Practolol halogenated derivatives, useful as myocardial beta adrenergic receptor markers, are of formula (I): in which R1 can be various groups, for example, an isopropyl group, R2 is a group of formula CH=CHX, CCX, O-(CH2)pX or OCH2CH=CHX, with X being an optionally radioactive halogen atom, R7 is O or NHCO and n is equal to 0, 1 or 2. When X is 123I, the derivatives of the invention can be used as markers for assaying myocardial beta adrenergic receptors.