首页> 外国专利> DERMATOLOGICAL COMPOSITION FOR PREVENTING THE DEVELOPMENT OF SYMPTOMS OF HYPERSENSITIVITY AND CUTANEOUS INTOLERANCE

DERMATOLOGICAL COMPOSITION FOR PREVENTING THE DEVELOPMENT OF SYMPTOMS OF HYPERSENSITIVITY AND CUTANEOUS INTOLERANCE

机译:防止过敏性皮肤病和皮肤不耐受症状发展的皮肤科成分

摘要

Dermatological and/or cosmetic compositions allowing the appearance of the symptoms of hypersensitivity and cutaneous intolerance to be avoided, comprise an effective combination of microbial proliferation inhibitors containing (a) a first microbial proliferation inhibitor which comprises an aqueous mixture of sodium polyacrylate, at least one polyol and at least one glycol compound of formula (1): R1-O-O(R2-O)nR3 in which R1 and R3 are independently H or a straight or branched C1-C5 alkyl group; R2 is a straight or branched C1-C5 aklylene group and n is between 1 and 400,000, and (b) a second microbial proliferation inhibitor which comprises at least one monoalkyl glycerine ether or an ester thereof of formula (II): R4OCH2CH(OH)CH2OR5 which R4 is a straight or branched chain alkyl group containing 6 to 24 carbon atoms and R5 is H or a straight or branched alkanoyl group containing 8 to 24 carbon atoms. The invention relates to the local or topical application of this composition as well as its use as a medicament, in particular for the treatment of the symptoms of hypersensitivity and cutaneous intolerance, psoriasis, atopy, acne and cutaneous ageing or for the prevention of the symptoms of benign estival light eruption.
机译:皮肤病学和/或化妆品组合物,其避免出现超敏反应和皮肤耐受不良的症状,其包含微生物增殖抑制剂的有效组合,所述微生物增殖抑制剂包含(a)第一微生物增殖抑制剂,所述第一微生物增殖抑制剂包含聚丙烯酸钠的水混合物,至少一种多元醇和至少一种式(1)的二醇化合物:R1-OO(R2-O)nR3,其中R1和R3独立地为H或直链或支链的C1-C5烷基; R 2为直链或支链的C 1 -C 5亚烷基,n为1至400,000,和(b)第二种微生物增殖抑制剂,其包含至少一种式(II)的单烷基甘油醚或其酯:R 4 OCH 2 CH(OH) CH 2 OR 5,其中R 4为含有6至24个碳原子的直链或支链烷基,R 5为H或含有8至24个碳原子的直链或支链烷酰基。本发明涉及该组合物的局部或局部应用以及其作为药物的用途,特别是用于治疗过敏性和皮肤不耐受,牛皮癣,特应性,痤疮和皮肤老化的症状或用于预防症状良性节食性火山爆发。

著录项

  • 公开/公告号FR2767697A1

    专利类型

  • 公开/公告日1999-03-05

    原文格式PDF

  • 申请/专利权人 THE BOOTS CY PLC;

    申请/专利号FR19970010866

  • 发明设计人 FRUCTUS ALAIN;BOBIER RIVAL CARINE;

    申请日1997-09-01

  • 分类号A61K31/78;A61K7/48;

  • 国家 FR

  • 入库时间 2022-08-22 02:10:27

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