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Megabase transcript map: novel sequences and antibodies thereto

机译:Megabase转录图谱:新序列及其抗体

摘要

A fine structure map of the 1 megabase region surrounding the candidate HH gene is provided, along with 250 KB of DNA sequence and 8 loci corresponding to candidate genes within the 1 megabase region. These loci are useful as genetic markers for further mapping studies. Additionally, the eight cDNA sequences corresponding to those loci are useful, for example, for the isolation of other genes in putative gene families, and as probes for diagnostic assays. Additionally, the proteins encoded by those cDNAs are useful in the generation of antibodies for analysis of gene expression and in diagnostic assays, and in the purification of related proteins.
机译:提供了围绕候选HH基因的1兆碱基区域的精细结构图,以及250 KB的DNA序列和对应于1兆碱基区域内候选基因的8个基因座。这些基因座可用作进一步作图研究的遗传标记。另外,对应于那些基因座的八个cDNA序列可用于例如分离推定基因家族中的其他基因,以及用作诊断测定的探针。另外,由那些cDNA编码的蛋白质可用于产生抗体以用于基因表达分析和诊断测定,以及用于相关蛋白质的纯化。

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