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Detection of prostate and other cancers by assaying for cancer- specific antigens having linked oligosaccharides which are at least triantennary

机译:通过检测具有至少三天线连接的寡糖的癌特异性抗原来检测前列腺癌和其他癌症

摘要

A process for assaying for cancer of the prostate, comprising assaying a sample derived from a human for prostate specific antigen having a linked oligosaccharide which is at least triantennary. The assay may employ a binding molecule which binds to oligosaccharides that are at least triantennary, but does not bind to oligosaccharides that are monoantennary or diantennary. Such binding molecule may be a lectin such as PHA-L or an antibody to an oligosaccharide that is at least triantennary.
机译:一种测定前列腺癌的方法,其包括测定来自人的样品的前列腺特异性抗原,该抗原具有至少三天线连接的寡糖。该测定法可以使用结合分子,该结合分子与至少三触角的寡糖结合,但不与单触角或双触角的寡糖结合。这样的结合分子可以是凝集素,例如PHA-L,或者是针对至少三天线的寡糖的抗体。

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