Methoxyoxalamido and succinimido precursors for nucleophilic addition to nucleosides, nucleotides and oligonucleotides

摘要

Moieties, including a 2'-methoxyoxalamido and N-succinimido moieties, were incorporated into a compound, particularly an oligonucleotide molecule. The moieties were shown to be useful precursors for the post synthetic introduction of various functional additives.