首页> 外国专利> Isolated nucleic acid encoding G-protein coupled receptor (HTADX50)

Isolated nucleic acid encoding G-protein coupled receptor (HTADX50)

机译:分离的编码G蛋白偶联受体(HTADX50)的核酸

摘要

HTADX50 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HTADX50 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
机译:公开了HTADX50多肽和多核苷酸以及通过重组技术产生这种多肽的方法。还公开了在设计方案中利用HTTAX50多肽和多核苷酸的方法,该方案用于治疗感染,例如细菌,真菌,原生动物和病毒感染,特别是由HIV-1或HIV-2引起的感染。疼痛;癌症;厌食症贪食症哮喘;帕金森氏病;急性心力衰竭;低血压高血压;尿retention留骨质疏松症心绞痛;心肌梗塞;溃疡;哮喘;过敏前列腺肥大;精神病和神经疾病,包括焦虑症,精神分裂症,躁狂抑郁症,ir妄,痴呆,严重智力低下和运动障碍,例如亨廷顿氏病或吉尔斯·德·图雷特综合症,以及针对此类疾病的诊断方法。

著录项

  • 公开/公告号US5910430A

    专利类型

  • 公开/公告日1999-06-08

    原文格式PDF

  • 申请/专利权人 SMITHKLINE BEECHAM CORPORATION;

    申请/专利号US19970788750

  • 发明设计人 DERK J. BERGSMA;CATHERINE E. ELLIS;

    申请日1997-01-24

  • 分类号C12N15/12;C12N15/62;

  • 国家 US

  • 入库时间 2022-08-22 02:08:02

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