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Camptothecin compounds with combined topoisomerase I inhibition and DNA alkylation properties
Camptothecin compounds with combined topoisomerase I inhibition and DNA alkylation properties
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机译:喜树碱类化合物具有拓扑异构酶I抑制和DNA烷基化特性的组合
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摘要
Camptothecin compounds having a --CH.sub.2 --L group are effective anti-tumor compounds. These compounds inhibit the enzyme topoisomerase I and DNA of associated topoisomerase I-DNA complexes.
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