Simple micro method for concentration and desalting utilizing a hollow fiber, with special reference to capillary electrophoresis

摘要

A dilute aqueous solution in microvolume quantity containing water soluble substances is concentrated by placing the solution in a length of hollow fiber whose wall contains pores sized to selectively pass water, while replenishing the fiber volume with additional solution at a rate approximately equal to the rate that the water passes through the fiber wall. A zone of concentrated solution is formed within the fiber, and the concentrated solution is then recoverable from the zone.