首页> 外国专利> Vectors carrying coding sequence for the SpsB protein of Staphylococcus aureus

Vectors carrying coding sequence for the SpsB protein of Staphylococcus aureus

机译:带有金黄色葡萄球菌SpsB蛋白编码序列的载体

摘要

spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections. Antagonists against such spsB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsB and for detecting the polypeptide in a host.
机译:公开了spsB多肽和编码此类spsB的DNA(RNA)以及通过重组技术生产此类多肽的方法。还公开了利用这种spsB治疗感染,特别是细菌感染的方法。还公开了针对这种spsB的拮抗剂及其在治疗感染,特别是细菌感染中的用途。还公开了用于检测与宿主中spsB核酸序列和多肽的存在有关的疾病的诊断测定法。还公开了用于检测编码spsB的多核苷酸和用于检测宿主中的多肽的诊断测定。

著录项

  • 公开/公告号US5977085A

    专利类型

  • 公开/公告日1999-11-02

    原文格式PDF

  • 申请/专利权人 SMITHKLINE BEECHAM P.L.C.;

    申请/专利号US19970940767

  • 发明设计人 MICHAEL T. BLACK;KAREN M. ODWYER;

    申请日1997-09-30

  • 分类号A61K48/00;C12N15/31;C12N15/57;C12N15/63;

  • 国家 US

  • 入库时间 2022-08-22 02:06:53

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