Way of increasing the riboflavin content in spray-dried discharges from riboflavin fermentations

摘要

A process for increasing the riboflavin content in spray-dried discharges from riboflavin fermentations comprises inducing the lysis of the cells contained in the fermentation discharge by specific production or activation of enzymes which break down the cell walls and proteins. This autolysis can be induced in the riboflavin-producing strains of Ashbya gossypii, Eremothecium ashbyii and other microorganisms by incubation at from 35 to 55° C. with substantial exclusion of oxygen for from 6 to 28 hours.