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Application of the novel DNA fragment as a sequence coding for the signal peptide on secretion of the mature protein by recombinant yeast expression cassette, transformed yeasts and process for producing a protein corresponding to the
Application of the novel DNA fragment as a sequence coding for the signal peptide on secretion of the mature protein by recombinant yeast expression cassette, transformed yeasts and process for producing a protein corresponding to the
The invention relates to new DNA fragments and to their application as a DNA coding fragment for a signal peptide which can be used for the secretion of proteins, said peptide including a sequence of amino-acids which show a degree of correspondence of at least 60 % with the sequence of amino-acids (I) or (II), preferably with the sequence (II). The sequences (I) and (II) are as follows: (I) Arg-Phe-Ser-Thr-Thr-Leu-Ala-Thr-Ala-Ala-Thr-Ala-Leu-Phe-Phe-Thr-Ala-Ser-Gln. (II) Arg-Phe-Ser-Thr-Thr-Leu-Ala-Thr-Ala-Ala-Thr-Ala-Leu-Phe-Phe-Thr-Ala-Ser-Gln-Val-Ser-Ala.
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