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Synthesis of 1,2,3-oxathiazolidine derivatives and thieno 3,2-c pyridine derivatives
Synthesis of 1,2,3-oxathiazolidine derivatives and thieno 3,2-c pyridine derivatives
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机译:1,2,3-恶唑烷衍生物和噻吩并[3,2-c]吡啶衍生物的合成
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摘要
Compounds of the formula: CHEM wherein: A is oxo or dioxo; R1, R2 and R3 are independently hydrogen or lower alkyl of one to six carbon atoms; R4, R5, R6 and R7 are independently hydrogen, lower alkyl of one to six carbon atoms, alkoxy, acyl or halo; are advantageously converted to thieno[3,2-c]pyridine derivatives and the pharmaceutically acceptable salts thereof, particularly ticlopidine hydrochloride.
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机译:式:的化合物其中:A是氧代或二氧代; R 1,R 2和R 3独立地为氢或1-6个碳原子的低级烷基。 R 4,R 5,R 6和R 7独立地为氢,1-6个碳原子的低级烷基,烷氧基,酰基或卤素;它们被有利地转化为噻吩并[3,2-c]吡啶衍生物及其药学上可接受的盐,特别是盐酸噻氯匹定。
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