Active agent for controlling the transformation of Candida species, a dimorphic fungus

摘要

Based upon a finding that farnesoate separated, purified and identified from a supernatant obtained after the transition of mycelial form cells to yeast form cells has regulatory activity on the morphological transition of dimorphic fungi, it was found that terpenes each having at least one geranyl group as its main structure have regulatory activity on the morphological transition. Thus is provided a regulatory agent on the morphological transition of dimorphic fungi, which transits their form as yeast form cells to mycelial form cells, and then to yeast form cells.