首页> 外国专利> Method for the Treatment or prevention of Pain and inflammatory processes and diseases, Pharmaceutical composition for use in the packaging, in the proceedings

Method for the Treatment or prevention of Pain and inflammatory processes and diseases, Pharmaceutical composition for use in the packaging, in the proceedings

机译:治疗或预防疼痛和炎症过程及疾病的方法,包装中使用的药物组合物,在诉讼中

摘要

To treat or prevent ignition process and diseases in dogs caused by conductive oxygen-2 cycle activity (COX-2), and to reduce or eliminate adverse side effects related to simultaneous inhibition of oxygen-1 cycle activity (COX-1), By selectively inhibiting the activity of COX-2 in COX-1 activity, wherein the selective proportion of COX-2: COX-1 is at least 3:1, according to the prebiotic inhibition level measured in whole blood;the inhibitor is a member selected from the group of anti-inflammatory compounds consisting essentially of derivatives of salicylic acid; dep-aminophen ol derivatives; indole and idenoacetic acids, heteroaryl acetic acids; arylpropionic acids; anthranilic acids; enolic acids; and alkanones; the inhibitor, in particular, is composed of elenantiomer (-) (S) of 6-chloro-alpha-methyl-9H-carbazol-2-acetic acid.
机译:通过选择性地治疗或预防由导电的氧2循环活性(COX-2)引起的犬着火过程和疾病,并减少或消除与同时抑制氧1循环活性(COX-1)相关的不良副作用。抑制COX-1活性的COX-1活性,其中COX-2∶COX-1的选择性比例至少为3∶1,这是根据全血中益生元抑制水平测得的;该抑制剂选自:一类主要由水杨酸衍生物组成的抗炎化合物;氨基苯酚衍生物;吲哚和异乙酸,杂芳基乙酸;芳基丙酸;邻氨基苯甲酸;烯醇酸和链烷酮;该抑制剂特别是由6-氯-α-甲基-9H-咔唑-2-乙酸的对映异构体(-)(S)组成。

著录项

  • 公开/公告号AR011726A1

    专利类型

  • 公开/公告日2000-08-30

    原文格式PDF

  • 申请/专利权人 PFIZER INC.;

    申请/专利号AR1998P102089

  • 发明设计人

    申请日1998-05-05

  • 分类号A61K31/40;A61P29/00;

  • 国家 AR

  • 入库时间 2022-08-22 01:57:32

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号